Sep 2014 - Melissa is awarded an ACS Research Scholars Grant
Aug 2014 - Kathy defends her Ph.D. thesis and graduates!
Aug 2014 - Melissa is awarded an NIH grant
Jun 2014 - Pedro defends his Ph.D. thesis and graduates!
May 2014 - Melissa receives an AHA grant
Jan 2014 - Nori receives the Dean's Award for Postdoctoral Research Excellence
Jan 2014 - Kathy is named an HHMI-UCI Graduate Fellow
Oct 2013 - Nori wins "Best Talk" at the Southern California Eukaryotic Pathogens Symposium
Sep 2013 - Kathy is selected for the Immunology Training Grant
Jul 2013 - Melissa is awarded a CRCC grant and a Hellman Fellows grant
Jun 2013 - Pedro receives a President's Dissertation Year Fellowship
Apr 2013 - Kathy is awarded "Best Talk" at the Woods Hole Immunoparasitology Meeting
Apr 2013 - Lanny receives a fellowship to attend the Woods Hole Immunoparasitology Meeting
Mar 2013 - Melissa is awarded a School of Biological Sciences Faculty Research Grant
Mar 2013 - Nori wins 1st prize for "Best Talk" (and an iPad!) at the Molecular Biology & Biochemistry Retreat, and Lanny wins runner-up for "Best Poster"
Nov 2012 - Kathy wins 1st prize for "Best Talk" at the UCI Immunology Fair, and Lanny, Pedro, and Nori present research posters
Nov 2012 - Nori receives an AHA Postdoctoral Fellowship
Nov 2012 - Kathy, Lanny, Pedro, and Nori present their research at the Southern California Eukaryotic Pathogens Meeting
Oct 2012 - Kathy presents her research at the La Jolla Immunology Conference
Aug 2012 - Datta is awarded a UROP Fellowship for undergraduate research
Jun 2012 - Melissa receives the Golden Apple Award for Teaching Excellence from the School of Biological Sciences
Jun 2012 - Melissa presents at the Gordon Conference on Host-Parasite Interactions
May 2012 - Pedro is awarded the UCI Graduate Division Faculty-Mentor Fellowship
Sep 2011 - Melissa receives an NIH (NICHD) Young Investigator Award of the Perinatal Research Society
Welcome to our lab!
We study host-pathogen interactions and immunity to infection. Our research focuses on the intracellular protozoan parasite Toxoplasma gondii, which infects an estimated one third of the human population worldwide and virtually all warm-blooded animals. In immune competent individuals, T. gondii is controlled by the immune system, and infections are typically mild or asymptomatic. The parasite establishes a chronic infection, however, which persists in various tissues in the body, including the brain, heart, and eye. In immune suppressed individuals, T. gondii can cause severe, life-threatening neurological disease.
We are particularly interested in the balance between host defense and disease progression, which reinforces the complex relationship of the immune response with the parasite. The goal of our research is to define the cellular and molecular interactions between T. gondii and host immune cells to better understand the development of disease and to facilitate the design of more effective anti-parasite therapeutics.