Publications

Gov L, Schneider CA, Lima TS, Pandori W, Lodoen MB.
NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes during Toxoplasma gondii Infection.
J Immunol. 2017 Sep 13. pii: ji1700245. doi: 10.4049/jimmunol.1700245. [Epub ahead of print]

Chen EY, Chu S, Gov L, Kim YK, Lodoen MB, Tenner AJ, Liu WF.
CD200 modulates macrophage cytokine secretion and phagocytosis in response to poly(lactic co-glycolic acid) microparticles and films.
J Mater Chem B Mater Biol Med. 2017. 5:1574-1584.

Konradt C, Ueno N, Christian DA, Delong JH, Pritchard GH, Herz J, Bzik DJ, Koshy AA, McGavern DB,
Lodoen MB, Hunter CA.
Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system.
Nature Microbiol. 2016. 1:16001.

Ueno N, Lodoen MB.
From the blood to the brain: avenues of eukaryotic pathogen dissemination to the central nervous system.
Curr Opin Microbiol. 2015. 26:53-9.

Ueno N, Lodoen MB, Hickey GL, Robey EA, Coombes JL.
Toxoplasma gondii-infected natural killer cells display a hypermotility phenotype in vivo.
Immunol Cell Biol. 2015. 93:508-13.

Harker KS, Ueno N, Lodoen MB.
Toxoplasma gondii dissemination: a parasite's journey through the infected host.
Parasite Immunol. 2015. 37:141-9.

Morgado P, Sudarshana DM, Gov L, Harker KS, Lam T, Casali P, Boyle JP, Lodoen MB.
Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses.
Infect Immun. 2014. 82:4047-55.

Shastri AJ, Marino ND, Franco M, Lodoen MB, Boothroyd JC.
GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response.
Infect Immun. 2014. 82:2595-605.

Harker KS, Jivan E, McWhorter FY, Liu WF, Lodoen MB.
Shear forces enhance Toxoplasma gondii tachyzoite motility on vascular endothelium.
mBio. 2014. 5:e01111-13.

Ueno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB.
Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers.
Cell Microbiol. 2014. 16:580-95.

Gov L, Karimzadeh A, Ueno N, Lodoen MB.
Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15.
mBio. 2013. 4(4).

Harker KS, Ueno N, Wang T, Bonhomme C, Liu W, Lodoen MB.
Toxoplasma gondii modulates the dynamics of human monocyte adhesion to vascular endothelium under fluidic shear stress.
J Leukoc Biol. 2013. 93:789-800.

Morgado P, Ong YC, Boothroyd JC, Lodoen MB.
Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction.
Infect Immun. 2011. 79:4401-12.

Koshy AA, Fouts AE, Lodoen MB, Alkan O, Blau HM, Boothroyd JC.
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions.
Nature Methods. 2010. 7:307-9.

Ravindran S, Lodoen MB, Verhelst SH, Bogyo M, Boothroyd JC.
4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion.
PLoS One. 2009. 4:e8143.

Lodoen MB, Gerke C, Boothroyd JC.
A highly sensitive FRET-based approach reveals secretion of the actin-binding protein toxofilin during Toxoplasma gondii infection.
Cell Microbiol. 2010. 12:55-66.

Kielczewska A, Pyzik M, Sun T, Krmpotic A, Lodoen MB, Munks MW, Babic M, Hill AB, Koszinowski UH, Jonjic S, Lanier LL, Vidal SM.
Ly49P recognition of cytomegalovirus-infected cells expressing H2-Dk and CMV-encoded m04 correlates with the NK cell antiviral response.
J Exp Med. 2009. 206:515-23.

Walsh KB, Lodoen MB, Edwards RA, Lanier LL, Lane TE.
Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease.
J Virol. 2008. 82:3021-30.

Walsh KB, Lodoen MB, Lanier LL, Lane TE.
NKG2D signaling and host defense after mouse hepatitis virus infection of the central nervous system.
Adv Exp Med Biol. 2006. 581:369-72.

Lodoen MB, Lanier LL.
Natural killer cells as an initial defense against pathogens.
Curr Opin Immunol. 2006. 18:391-8.

Desrosiers MP, Kielczewska A, Loredo-Osti JC, Adam SG, Makrigiannis AP, Lemieux S, Pham T, Lodoen MB, Morgan K, Lanier LL, Vidal SM. Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection.
Nature Genet. 2005. 37:593-9.

Lodoen MB, Lanier LL.
Viral modulation of NK cell immunity.
Nature Rev Microbiol. 2005. 3:59-69.

Lodoen MB, Abenes G, Umamoto S, Houchins JP, Liu F, Lanier LL.
The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions.
J Exp Med. 2004. 200:1075-81.

Lodoen M, Ogasawara K, Hamerman JA, Arase H, Houchins JP, Mocarski ES, Lanier LL.
NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.
J Exp Med. 2003. 197:1245-53.